Back to Search Results

Diabetic ketoacidosis in acromegaly; a rare complication precipitated by corticosteroid use.

Department of Endocrinology, Austin Health, Level 2 Centaur Building, Repatriation Campus Heidelberg West, Victoria 3084, Australia. Department of Endocrinology, Austin Health, Level 2 Centaur Building, Repatriation Campus Heidelberg West, Victoria 3084, Australia; Department of Medicine, Austin Health and the University of Melbourne (Austin Campus), Parkville, VIC 3010, Australia. Department of Medicine, Austin Health and the University of Melbourne (Austin Campus), Parkville, VIC 3010, Australia. Department of Endocrinology, Austin Health, Level 2 Centaur Building, Repatriation Campus Heidelberg West, Victoria 3084, Australia; Department of Medicine, Austin Health and the University of Melbourne (Austin Campus), Parkville, VIC 3010, Australia. Electronic address: elif.ekinci@unimelb.edu.au.

Diabetes research and clinical practice. 2017;:29-37
Full text from:

Other resources

Abstract

Diabetic ketoacidosis has been described in the literature as a rare possible initial presentation of acromegaly before a diagnosis of acromegaly is eventually made. Indeed, diabetic ketoacidosis is a recognised complication of acromegaly. There are a number of factors that can predispose patients with acromegaly to diabetes as well as to diabetic ketoacidosis. These include high levels of growth hormone and insulin-like growth factor 1 in acromegaly and the effect on glycaemia by medications used in the management of acromegaly. Ketoacidosis has been described in patients with acromegaly even without the presence of an underlying autoimmune diabetes. Patients with acromegaly and ketoacidosis often respond to treatment and may not require long-term insulin.

Methodological quality

Publication Type : Case Reports ; Review

Metadata